7 Best Toenail Fungus Over The Counter Treatments[2021]

Do your toenails turn yellow, split, or peel? If so, you could be one of over an estimated 40 million Americans who live with toenail fungus. The good news is, you don’t have to live like this. A number of remedies can help you walk with confidence. Here are 7 best toenail fungus over the counter treatments that you can buy at your local drugstore.

feet, toes, woman - toenail fungus over the counter treatments

Nail fungus is the most common nail problem, and the treatment can be very difficult. Aside from the ugly appearance – nail fungus can also be quite painful. Toenail fungus spreads fast and can be very hard to get rid of.

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What is toenail fungus?

Toenail fungus, also known as onychomycosis, is a common fungal infection of the toenail. The most visible symptom is a white, light brown, or yellow discoloration of your toenail. It can spread causing the nails to thicken or crack.

With summertime just around the corner, it’s time to think about beautiful swimsuits and sandals. Toenail fungus isn’t what anyone wants to see when you looking at your feet. Good news! There are several treatments you can available for your to try.

Prescription drugs to treat toenail fungus

Prescription oral antifungals, such as Lamisil (terbinafine) or Diflucan (fluconazole), are the most popular drugs used to treat toenail fungus. These treatments are quite effective but can cause serious side effects, like an upset stomach and dizziness, as well as severe skin problems and jaundice.

Because of these side effects, many people try home remedies instead.

Here are 7 of the most popular toenail fungus over the counter treatments.

Even though over the counter treatments may not be as effective as a medical prescription, they are definitely worth considering:


Tolnaftate (INN) is a synthetic thiocarbamate used as an anti-fungal agent that may be sold without medical prescription. This is popular in OTC products for athlete’s foot, ringworm, and jock itch. It comes in a cream, powder, spray, or liquid. Treatment should be for at least 2 weeks after symptoms disappear.

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Undecylenic Acid

Undecylenic acid belongs to the group of medicines called antifungals. It is used to treat some types of fungus infections. Lately, undecylenic acid has been replaced by newer and more effective medicines for the treatment of fungus infections. This anti-fungal medicine is the main ingredient in many over-the-counter products. You can find undecylenic acid in commonly sold products as a liquid or a polish you paint onto your nails.

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Clotrimazole is an antifungal medicine. It’s used to treat skin infections caused by a fungus (yeast). You’ll find clotrimazole in many over the counter yeast infection creams. However, it’s also used to treat toenail fungus. Research has found it worked for most of the patients who used it in a 12-week treatment period. It is available as a cream or lotion.

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Tea Tree Oil

Tea tree oil is an essential oil that can be used for several purposes, including keeping skin, hair, and nails healthy. This treatment comes from a tree in Australia. It’s a popular treatment for many conditions, including foot fungus. Recent research has shown tea tree oil to works as well as clotrimazole, which is found in many OTC treatments.

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Mentholated Cream

You may already use this common treatment for chest colds. However, did you know vapor rub is a popular home remedy for toenail fungus? While there is not a lot of research around using mentholated cream for the treatment of toenail fungus, but it does have its supporters.

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Snakeroot Extract

This fungus fighter comes from a plant, so don’t be nervous. There has been some feedback from users who tried this natural remedy found it worked almost as well as ciclopirox, a medicine used to treat skin infections caused by a fungus.

Baking Soda

In some studies, the use of sodium bicarbonate was shown to limit the growth of the most common types of fungi that cause skin and nail infections.

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Last update on 2022-06-22 / Affiliate links / Images from Amazon Product Advertising API